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KMID : 0043320020250010067
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Archives of Pharmacal Research
2002 Volume.25 No. 1 p.67 ~ p.70
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Effects of Opuntia ficus-indica var. Saboten Stem on Gastric Damages in Rats
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Lee EB
Moon YI/Hyun JE/Li DW
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Abstract
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The effects of the dried stem powder of Opuntia ficus-indica var. saboten (OF- s) were investigated on gastric lesion and ulcer models in rats. It showed signifcant inhibition in HCI·ethanolinduced gastric lesion at the doses of 200 and 600 mg/kg p.o. and in HCI·aspirin-induced gastric lesion at 600 m9/kg p.0. OF-s also Showed significant inhibition in indomethacin-induced gastric lesion at the doses of 200 and 600 mg/kg, p.o. However, it did not affect both the aspirin-induced and Shayulcers in rats. It also did not affect gastric juice secretion, acid output and pH. These data indicate that OF-s only possesses pronounced inhibitory action on gastric lesion without antiulcer activity in rats.
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KEYWORD
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